Proanthocyanidin Alleviates Liver Ischemia/Reperfusion Injury by Suppressing Autophagy and Apoptosis via the PPARα/PGC1α Signaling Pathway
نویسندگان
چکیده
Background and AimsHepatic ischemia-reperfusion injury (IRI) is a common pathophysiological phenomenon in clinical practice, which usually occurs liver transplantation, resection, severe trauma, hemorrhagic shock. Proanthocyanidin (PC), exerted from various plants with antioxidant, antitumor, antiaging activity, were administrated our study to investigate the underlying mechanism of its protective function on IRI.
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ژورنال
عنوان ژورنال: Journal of clinical and translational hepatology
سال: 2023
ISSN: ['2310-8819', '2225-0719']
DOI: https://doi.org/10.14218/jcth.2023.00071